Which DHT blocker should you choose? Selection guide by profile

What you must remember

The hormonal drop stems from an excess of DHT, produced by the 5-alpha-reductase enzyme. A DHT blocker acts on this conversion—but its effectiveness depends entirely on the nature of the extract used, information that almost no brand discloses. Our DHT Blocker® is based on a standardized extract of Serenoa repens , dosed at 300 mg per day.

  • A DHT blocker acts on the hormonal cause, not on the symptom
  • What matters is not the weight of the capsule but the nature of the extract
  • Our formula: 300 mg of standardized Serenoa repens extract per day
  • The hormonal decline has four mechanisms: a supplement alone only covers one of them.
Which DHT blocker should you choose? Selection guide by profile

Our DHT Blocker® Hormone Loss Relief formula contains 300 mg of standardized Serenoa repens extract per daily dose—a concentrated extract, not a berry powder. Here's why this distinction makes all the difference, and how to tell if a DHT blocker is actually dosed correctly.

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How does a DHT blocker work?

Androgenetic alopecia relies on a unique mechanism: the 5-alpha-reductase enzyme converts testosterone into DHT, which binds to genetically sensitive follicles and triggers their miniaturization. The hair regrows thinner and shorter, eventually ceasing to grow at all. A DHT blocker partially inhibits this enzyme and slows down the process.

  • It protects the follicles that are still active rather than awakening those that are dormant.
  • Its effect is proportional to the early intervention.
  • It remains active as long as it is maintained: when it stops, the conversion resumes.

When I formulated our DHT Blocker, I started with a simple observation: most supplements on the market list "saw palmetto" without ever specifying whether it's a standardized extract or just a simple berry powder. That's why we chose a concentrated extract of Serenoa repens , dosed at 300 mg per day. Consumers should be able to compare, not just take their word for it.

Dr. Julie PernetDoctor of Pharmacy & Certified Trichologist

What makes our DHT Blocker different

Two supplements labeled "300 mg of saw palmetto" can deliver radically different amounts of active ingredients. It all depends on the form of the extract: raw berry powder, concentrated extract, or standardized extract—information that almost no one discloses.

  • 300 mg of standardized extract of Serenoa repens per daily dose (2 capsules), equivalent to 1200 mg of plant
  • 2 million UFC of Lactobacillus acidophilus PBS066to support the assimilation of cofactors
  • A complete formula : green tea, ginseng, zinc, vitamins B6, B8 and D3
  • Made in France, to pharmaceutical grade
  • 180 capsules, enough for a 3-month coursethe duration of a hair cycle

Which DHT blocker is right for your hair loss profile?

Four situations cover the vast majority of cases:

  • Beginner fall, less than two years old — Now is the perfect time to act: our DHT Blocker® alone is often enough to preserve the remaining active follicles
  • Established hair loss in men, marked temples or vertex — our DHT Blocker® is part of a complete protocol, combined with topical action
  • Hormonal drop in women — Since finasteride is contraindicated in women of childbearing age, our DHT Blocker® is often the only accessible option, including in cases of PCOS or menopause
  • Reactive hair loss — stress, deficiency, season, postpartum — This is not the right product: you should be looking at the anti-reactive hair loss supplement

If your hair loss is reactive — stress, deficiency, season, postpartum — you should turn to the reactive hair loss supplement , not this one.

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Verified review

"I had been using minoxidil for years but with many side effects. I tried this
I tried the serum, thinking it wouldn't work... and yet! The bald spot on the back of my head has clearly filled in. Amazing!

Julien S., a customer for 4 months

Discover the solution

A DHT blocker is never enough on its own

The hormonal decline is not due to one mechanism but to four: hormonal conversion, low-grade inflammation around the follicle, ostium obstruction, and the skin barrier that prevents active ingredients from reaching the root. Our DHT Blocker addresses the first—the only one that no topically applied treatment can reach, since the conversion of testosterone to DHT is an internal process.

To cover the other three, it is combined with the active scrub, the pH 5 shampoo, and the micro-infusion of the hormonal anti-hair loss protocol . Each component targets a distinct mechanism: the effectiveness is synergistic, not simply additive.

Hormonal Anti-Hair Loss Protocol

Specifically acts on hormonal hair loss

€178,82€152,00

To remember

  • A DHT blocker acts on the hormonal cause, not on the symptom
  • What matters is not the weight of the capsule but the nature of the extract
  • Our formula: 300 mg of standardized Serenoa repens extract per day
  • The hormonal decline has four mechanisms: a supplement alone only covers one of them.

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F.A.Q

What is the best DHT blocker?
There is no absolute right choice: the best choice depends on how long you have had the hair loss, its location, your sex and your tolerance to the medication.
Natural DHT blocker or finasteride: which to choose?
If you're looking for a natural alternative to finasteride, our MakeMyMask DHT Blocker is formulated with naturally derived ingredients and is available without a prescription. It helps limit the effects of DHT on the hair follicle, while also being a drug-free option.

Unlike finasteride, our DHT Blocker does not require a prescription and does not have the same hormonal side effects associated with anti-DHT medications. It is therefore a natural alternative to incorporate into an anti-hair loss routine.
What dosage of saw palmetto should be taken per day?
Reference clinical studies use 320 mg per day of standardized liposterolic extract. The important figure is not the weight of the capsule but the nature of the extract—always check that it is a standardized extract and not a berry powder.
DHT blocker or minoxidil: which one really treats hair loss?
The blocker acts on the hormonal cause, while minoxidil addresses the symptom by prolonging the growth phase. They are not mutually exclusive: the best published results are obtained in combination, not with either one alone.
How long does it take for a DHT blocker to take effect?
Three months minimum, six to judge. The hair cycle imposes this timeframe: an active ingredient only acts on follicles entering the growth phase, and then the hair must become visible, at a rate of one centimeter per month.
What happens if you stop taking a DHT blocker?
The hair loss gradually resumes its course. Like all 5-alpha-reductase inhibitors, a blocker slows down androgenetic alopecia as long as it is taken: it does not cure it.
Does a DHT blocker work on advanced baldness?
It can stabilize hair loss and preserve remaining hair, but it doesn't revive a dormant follicle. The earlier the intervention, the more visible the result—this is the main prognostic factor.

Written by

Dr. Julie Pernet

Doctor of Pharmacy & Certified Trichologist. Doctor of Pharmacy and Trichologist, founder of the DermoPilaire MakeMyMask Laboratory. She develops skincare protocols focused on scalp health, based on microbiome science and pH balance.

Dr. Julie Pernet