Ariana Grande, Lady Gaga and androgenic alopecia: the protocol everyone is talking about

THEandrogenetic alopecia is the leading cause of chronic hair loss in adults. Long considered a taboo subject, particularly among women, it nevertheless affects millions of peopleincluding world-famous celebrities.

These last years, Lady Gaga et Ariana Grande both publicly discussed their problems with hair loss, thinning of hair and weakening of the scalp.

What is androgenetic alopecia?

THEandrogenetic alopecia is a hair loss of hormonal and genetic origin, linked to the sensitivity of hair follicles to DHT, a hormone derived from testosterone via the enzyme 5-alpha-reductase.

Pathophysiological mechanism 

• DHT binds to receptors in the follicle

• ELLE shortens the growth cycle (anagen phase)

• The hair becomes thinner, shorterthen gradually disappears

• They are talking about follicular miniaturization

Why our 4-step protocol is relevant in androgenetic alopecia

The common mistake in hormonal decline is to treat only the fiber or focus on a single lever.
However, androgenetic alopecia requires a holistically scalp + follicle + biological signaling + internal action on DHT.

1. Active Anti-Hair Loss Scrub : exfoliate and purify the scalp

In androgenetic alopecia, the scalp is often:

• congested,

• micro-inflamed,

• loaded with oxidized sebum.

Gentle exfoliation allows you to:

• de unclog the follicle,

• to improve oxygenation,

• to optimize the penetration of anti-hair loss active ingredients.

2. Anti-hair loss shampoo pH 5 : wash without damaging

An irritated scalp = inflammation = worsening hair loss.
An anti-hair loss shampoo formulated with a pH close to 5 allow :

• to preserve the skin barrier,

• to respect the microbiome

• to limit perifollicular micro-inflammation.

The link between pH, inflammation and hair loss is well documented (PubMed: Proksch E.).

3. Anti-Hair Loss Serum : acts on the 3 key markers of growth

A truly effective serum for androgenetic alopecia must act on:

• cell proliferation (e.g., Ki67)

• shoot signaling (β-catenin)

• follicular growth factors (IGF-1)

The objective:

• reduce the fall
• prolong the anagen phase
• stimulate better quality regrowth

These markers are widely used in ex vivo and clinical studies on hair growth (J Dermatol Sci).

4. DHT Blocker supplement: acts from the inside on the hormonal cause

Androgenetic alopecia being hormone-dependentInternal action is essential.
Un DHT Blocker When well-formulated, it allows:

• to partially inhibit the 5-alpha-reductase,

• to reduce the impact of DHT on the follicle,

• without the side effects of heavy drug treatments.

Numerous publications demonstrate the benefits of certain natural active ingredients in modulating DHT (e.g., Serenoa repens, zinc, etc.), even if Efficacy is highly dependent on dosage and bioavailability. an often underestimated point.

In short

• THEandrogenetic alopecia is a chronic, hormonal and multifactorial condition that affects millions of people and even well-known figures.

• Effective care relies on a complete strategy scalp, follicle, biological signaling and internal anti-DHT action.

• modern protocols are moving towards natural, microbiome-friendly and scientifically supported approaches, as a complement to or alternative to conventional treatments.